What is CONTRAVE?
Weight loss is not a one-size-fits-all approach. Learn how CONTRAVE can help you on your weight-loss journey.
- CONTRAVE is an FDA-approved weight-loss medication for people who are
overweight with at least one serious medical condition, including diabetes,
high blood pressure, etc., or those struggling with obesity. - It is uniquely designed to reduce hunger and control cravings,
so you can lose weight and keep it off when combined with diet and exercise. - It is not a controlled substance, scheduled drug, or stimulant.
- CONTRAVE is the #1 branded oral weight loss medication.**
**Based on the number of prescription fills for a brand name weight-loss drug in the IQVIA database July 2021 – June 2022
How CONTRAVE works
CONTRAVE targets 2 areas of the
brain that cause hunger and cravings†
Hunger
happens when your brain tells you that it needs nutrition and that any food will satisfy this need.
Cravings
happen when your brain wants specific foods, even though you may not feel hungry.
†Other areas of the brain may be involved. The exact neurochemical effects of CONTRAVE leading to weight loss are not fully understood.
The Science Behind CONTRAVE
There’s A Scientific Reason You Are Struggling To Lose Weight & Keep it Off
Through science, we can better understand this challenge because it turns out your brain may be working against you by sending hunger signals or triggering cravings, even when you’re not hungry.
Our brains play a role in the struggle to lose weight:
The hunger center (hypothalamus) can increase hunger, telling you to eat again or eat more
The mesolimbic circuit or reward system can create cravings that seem uncontrollable even when you’re not hungry
CONTRAVE was studied for efficacy and safety in several clinical trials
The efficacy and safety of CONTRAVE were assessed in the 56-week CONTRAVE Obesity Research (COR) clinical studies.
3
56-week
studies
2,322
patients